Abstract: Objective : To systematically review the research progress of suicide in elderly cancer patients, explore its epidemiological status, multi-dimensional influencing factors and interaction mechanism, evaluate the effectiveness of existing intervention strategies, and provide a basis for future research directions and clinical practice recommendations. Methods : The influencing factors and effective intervention measures of suicide risk in elderly cancer patients were summarized by combing relevant studies. Results : Elderly cancer patients are at high risk of suicide, and the risk is affected by many factors such as cancer type and diagnosis stage. The influencing factors cover three dimensions of biology, psychology and society, and the risk is formed through the interaction of ' biology-psychology-society ' model. Among them, early integrated palliative care can indirectly reduce the risk of suicide. Digital health intervention has potential but needs more evidence, but there is insufficient research on direct intervention for suicidal ideation.Conclusion : At present, there are some problems in the research on suicide in elderly cancer patients, such as inaccurate data, insufficient understanding of the mechanism, and lack of evidence for intervention. It is recommended to establish a standardized data monitoring and sharing system, conduct longitudinal cohort studies, and design multi-mode preventive intervention programs to build a safety protection network and reduce the risk of suicide in this group.