Objective: The purpose of this survey is to have an understanding of the current situation of nurses’ experience in taking care of the deathbed patients and their abilities of coping with death in a hospital in Macao and explore its impact on them. Methodology: A cross-sectional questionnaire was used to collect data from nurses, and social demographic analysis and inferential analysis were carried out. Results: The average score of death-coping abilities of nurses in a hospital in Macao is 125.4±17. The highest score among all dimensions of death-coping abilities is the ability to think and express death resulting in 21.37±3.68. The lowest score is the ability to manage depressions when experiencing loss resulting in 11.22±2.01. There are significant differences between the deathcoping abilities of nurses with years of service and how experienced they are in deathbed patients caring. The results also showed that nurses with more experience dealing with deathbed patients caring scored remarkably higher than those with no such experience when coping with death (p＜0.05). Conclusion: Conclusion: The scores of nurses’ death response ability in a hospital in Macau are in the middle level. Nurses at a higher age, having more years of service, more experience in taking care of terminal patients, are able to deal with death better. In addition, Nurses have strong ability to think about death and weak ability to deal after facing a loss. Recommendation: Multi- dimensional discussion about nurses’ death-coping abilities should be enforced. More supportive resources to relieve stress and more training courses should be made available for clinical nurses.